How sun exposure improves our immune function

By Dr. Mercola

Mounting research confirms that sun avoidance may be at the heart of a large number of health problems. Not only does your body produce vitamin D in response to sun exposure on bare skin, but sunlight also produces a number of other health benefits that are unrelated to vitamin D production.

In fact, humans appear to have a lot in common with plants in this regard — we both need direct sun exposure in order to optimally thrive, and while artificial lighting sources offering specific light spectrums may be helpful for various problems, ideally we need the full spectrum of light that natural sunlight offers.

Most recently, researchers at Georgetown University Medical Center (GUMC) published a laboratory study using cells in petri dishes, showing that exposure to blue and ultraviolet (UV) light increases T cell activity — white blood cells involved in immune function and fighting infections.

Sunlight is a natural immune booster

This is thought to be the first study showing an impact of light on this particular type of immune cell, so more research is needed to verify the results. However, there’s plenty of evidence in the medical literature confirming that sunlight has immune-boosting properties.

In this study, light was found to stimulate the production of hydrogen peroxide, which boosted the activity of T lymphocytes. As little as five to 10 minutes of sun exposure were needed to boost immune cell activity. As noted in one news report:

Given the large surface area of human skin, all of the T cells present in skin could potentially benefit from this phenomenon through exposure to blue light, the researchers suggest.

Note that vitamin D is only produced in the body via exposure to UVB rays, which can be harmful in cases of prolonged sun exposure.

If blue light from the sun’s rays is capable of energizing infection-fighting T cells, it could be a potential means of treatment for boosting immunity in many patients, the researchers conclude.”

While the researchers appear hopeful that blue light alone might be a valuable immune-boosting treatment, it’s important to realize that the biological effects of light can be very complex, and it’s important to get it right.

As explained by Dr. Alexander Wunsch, a world class expert on photobiology, excessive exposure to blue light — such as that from LED lighting, which is primarily blue and devoid of near-infrared found in sunlight and incandescent lighting — can be quite harmful, and may be a significant risk factor for age-related macular degeneration (AMD).

The healthiest blue light is from the sun, as it is balanced by near-infrared radiation, which has many important biological functions. Importantly, near-infrared radiation will activate cytochrome C oxidase in your mitochondria and help to optimize ATP production.

T cells are intrinsically photosensitive

For a long time, it was believed mammals only had photosensitive cells in the eye. We’re now finding photosensitive cells in many other areas of the human body.

As noted by the authors, this study demonstrates that “T lymphocytes possess intrinsic photosensitivity and this property may enhance their motility on skin.” In other words, T cells sense and respond to light.

Blue light specifically triggers the production of hydrogen peroxide (H2O2) in T cells, which triggers a chemical cascade that results in increased T cell motility. The increased motility or activity, in turn, allows the immune cells to function better.

Interestingly, once the T cells are activated they also alter their antioxidant capacity — an effect that appears to allow for greater H2O2 production in response to light.

The spectral sensitivity of T cells peaked at both ~350 nanometers (nm), which is in the ultraviolet A (UVA) range, and ~470 nm, which is in the blue spectrum. The latter (470 nm light) has previously been shown to kill methicillin-resistant Staphylococcus aureus (MRSA) in vitro.

According to lead author Gerard Ahern, Ph.D., an associate professor at the Department of Pharmacology and Physiology in Georgetown, some of the immunity benefits typically attributed to vitamin D may actually be due to this new-found mechanism.

While there may be some truth to that, previous research has teased out a number of different mechanisms for vitamin D’s activity, including its bactericidal and immune-boosting effects.

For example, researchers have found vitamin D acts directly on the beta defensin 2 gene (which encodes an antimicrobial peptide) and the NOD2 gene (which alerts cells to the presence of invading microbes). Vitamin D is also involved in the production of over 200 antimicrobial peptides that help fight all sorts of infections.

Other health benefits of sunlight unrelated to vitamin D

This certainly isn’t the first time sunlight has been shown to produce biological effects that are important for good health. Other health benefits of sun exposure include the following.

To learn more, I recommend reading through “Sunlight: For Better or For Worse? A Review of Positive and Negative Effects of Sun Exposure,” published in the journal Cancer Research Frontiers.

This is probably the most well-known benefit of sun exposure, and there’s a robust body of scientific research confirming the many benefits of optimal vitamin D levels.

Importantly, the evidence now clearly shows that once you reach a serum vitamin D level of 40 ng/ml, your risk for cancer plunges by 67 percent, compared to having a level of 20 ng/ml or less.

Even the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine (formerly Institute of Medicine, IOM) has reported an association between vitamin D and overall mortality risk from all causes, including cancer.

Vitamin D also increases your chances of surviving cancer if you do get it,and this includes melanoma patients. Vitamin D is also important for your bone health, cognitive function, immune function and healthy pregnancy and infant development.

The overall health benefits of vitamin D are so significant, a Swedish research team recently warned that “avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking.”

Anchoring your circadian rhythm

Spending time in bright midday sun helps anchor your circadian rhythm, which is important for optimal sleep. The vitamin D you get from sun exposure can also play a role in your sleep.

Surprising as it sounds, scientists have found vitamin D deficiency raises your risk of obstructive sleep apnea In one study, 98 percent of patients with sleep apnea had vitamin D deficiency, and the more severe the sleep apnea, the more severe the deficiency.

Lowering high blood pressure and reducing risk for heart disease and cancer

Research has shown that when sunlight strikes your skin, nitric oxide (NO) is released into your bloodstream. NO is a powerful blood pressure lowering compound that helps protect your cardiovascular system, cutting your risk for both heart attacks and stroke.

UVB light lowers blood pressure by dilating blood vessels specifically the capillaries in your skin. This directs about 60 percent of your blood flow there. This then allows the sun’s rays to easily penetrate into your blood.

Sunlight has UV rays known to be germicidal and can help kill infections in your blood. This aspect of sunlight was used to treat tuberculosis in the late 19th and early 20th centuries, even awarding a Nobel prize to Finson in 1903 for this work.

According to one 2013 study, for every single skin cancer death, 60 to 100 people die from stroke or heart disease related to hypertension. So your risk of dying from heart disease or stroke is on average 80 times greater than your risk of dying from skin cancer.

While higher vitamin D levels correlate with lower rates of cardiovascular disease, oral vitamin D supplements do not appear to benefit blood pressure, and the fact that supplements do not increase nitric oxide may be the reason for this.

Modulating genetic expression related to your inflammatory response

Sunlight also appears to alter genetic expression. Cambridge University scientists recently showed that the expression of 28 percent of the human genetic make-up varies from season to season. Some of those genetic changes affect your inflammatory responses.

During winter months, inflammatory immune-system genes are activated, which helps combat infectious microbes, and during the summer the activity of anti-inflammatory gene activity increases.

In essence, during the summer your body begins to combat the damage incurred by the inflammation produced when your immune system is on red alert. But for that, you need sun exposure.

Preventing infectious diseases

Both UV light itself and the vitamin D produced when your skin is exposed to it have potent antimicrobial effects.

While vitamin D increases production of naturally occurring antimicrobial peptides that destroy the cell walls of viruses and bacteria, UV light also increases blood levels of infection-destroying lymphocytes (white blood cells).

Besides boosting rates of cardiovascular disease, widespread sun avoidance may also be responsible for the reemergence of tuberculosis (TB), which now kills about 4,100 people every single day.

In 2014, there were 1.5 million TB-related deaths worldwide, making it the No. 1 infectious disease out there. Compare that to the 55,100 who die from melanoma each year (worldwide).

UV light, especially blue light, also acts as a potent disinfectant of your environment. Research has found UV light can reduce the spread of tuberculosis in hospital wards and waiting rooms by 70 percent,and helps kill 90 percent of drug-resistant bacteria in hospital rooms.

Data suggests UV light at 254 nm can kill drug-resistant strains of S. aureus and E. faecalis in as little as five seconds.

Boosting brain serotonin, thereby improving mood and mental health

Sun exposure boosts the feel-good brain chemical serotonin, which is in part why you feel better after spending some time in the sun.

Light therapy has long been the go-to treatment for seasonal affective disorder (SAD), and more recent research suggests it can be useful in the treatment of major depression as well. Schizophrenia has also been linked to maternal lack of sun exposure during pregnancy.

Importantly, you also have serotonin in your gut, and here, vitamin D has been shown to combat inflammation caused by excessive gut serotonin.

In other words, sunlight and vitamin D both play intricate roles in the gut-brain axis, raising levels in the brain while lowering levels in your gut, thereby improving mood on the one hand, while reducing gut inflammation on the other.

To learn more about this, please see “New Discoveries May Unlock the Link Between Vitamin D Deficiency and Autism.”

Boosting testosterone and protecting male fertility

Sunlight helps boost men’s libido by affecting testosterone. Australian research reveals that men’s testosterone levels rise and fall with the seasons, peaking during August, and hitting their lowest levels in March.

Researchers at Johns Hopkins have also linked low vitamin D levels with an increased risk for erectile dysfunction (ED).

Boosting dopamine, thereby protecting against myopia

Australian researchers have found that kids who spend most of their days indoors have significantly higher rates of high degree myopia (short-sightedness).

As reported by The Daily Mail: “The researchers believe that the neurotransmitter dopamine is responsible. It is known to inhibit the excessive eyeball growth that causes myopia. Sunshine causes the retina to release more dopamine.”

The Bright World of the Gods

A real faery-tale from the mists of Avalon

Learn more and get it here


Please help us to continue supplying you with all the most up-to-date information on health and wellbeing – and also about how it is under attack. A small donation would make a huge difference to our research…Please give here.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.